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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH1 All Species: 9.7
Human Site: T205 Identified Species: 21.33
UniProt: O60610 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60610 NP_001073280.1 1272 141347 T205 L H D E K E E T A G S Y D S R
Chimpanzee Pan troglodytes XP_509808 1253 142880 G227 I N T A S K T G S L K R S R Q
Rhesus Macaque Macaca mulatta XP_001089232 1269 142127 T231 L H D E K E E T A G S Y D S R
Dog Lupus familis XP_857344 981 113022 V117 G K I Q E K I V K K N Q H K V
Cat Felis silvestris
Mouse Mus musculus O08808 1255 139325 T196 L H D E K E E T S G N Y D S R
Rat Rattus norvegicus NP_001100863 346 39403
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989541 1253 139246 E219 L L D K K Q Q E N I D K K N Q
Frog Xenopus laevis Q6NTV6 1099 121463 E184 R F S V I T N E L S S S D N V
Zebra Danio Brachydanio rerio XP_683813 932 105075 T68 H P T D P I S T Q T E L P V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 E182 S K N N A S Y E K I E F E A I
Honey Bee Apis mellifera XP_395654 1140 128906 L188 Q Y E C I R C L K A I M N N T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.5 91.8 43.2 N.A. 90.3 25.7 N.A. N.A. 53 27.2 40.4 N.A. 36.7 39.5 N.A. N.A.
Protein Similarity: 100 50 93.2 58.4 N.A. 93.4 26.3 N.A. N.A. 68.4 46.4 53.7 N.A. 54.8 58 N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 86.6 0 N.A. N.A. 20 13.3 6.6 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 100 0 N.A. N.A. 53.3 20 13.3 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 19 10 0 0 0 10 0 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 37 10 0 0 0 0 0 0 10 0 37 0 0 % D
% Glu: 0 0 10 28 10 28 28 28 0 0 19 0 10 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 0 28 0 0 0 0 0 % G
% His: 10 28 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 10 0 19 10 10 0 0 19 10 0 0 0 10 % I
% Lys: 0 19 0 10 37 19 0 0 28 10 10 10 10 10 0 % K
% Leu: 37 10 0 0 0 0 0 10 10 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 10 10 0 0 10 0 10 0 19 0 10 28 0 % N
% Pro: 0 10 0 0 10 0 0 0 0 0 0 0 10 0 10 % P
% Gln: 10 0 0 10 0 10 10 0 10 0 0 10 0 0 19 % Q
% Arg: 10 0 0 0 0 10 0 0 0 0 0 10 0 10 28 % R
% Ser: 10 0 10 0 10 10 10 0 19 10 28 10 10 28 0 % S
% Thr: 0 0 19 0 0 10 10 37 0 10 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 10 0 0 0 0 0 10 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 0 0 0 0 28 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _